Sydenham Street United Church is wheelchair accessible through two entrances:
- the lane-way entrance, off Sydenham Street where there is also a handicapped parking spot right beside that door;
- a extensive ramp that provides access through the William Street entrance to the church.
In 2017, an elevator was installed to take people to all floors of the building. At the same time, the washroom facilities were more than doubled, including gender-neutral washrooms. There are wheelchair-accessible washrooms on both floors.
In the sanctuary/venue, there are two spots reserved for wheelchairs.
Assisted hearing devices are available on request